Central Dogma of Molecular Biology Research Assignment (Essay Sample)

Central Dogma of Molecular BiologyNameInstitutionInstructorCourseDateIntroductionThe central dogma of molecular biology was put forward by Francis Crick in the year 1958 with the keystone of molecular biology to prove substantial over-simplification. It deals with detailed residue by residue sequential information transfer, and states that information can never be transferred from the protein to protein or the nucleic acid (Crick, 1970). This paper discusses three classification of information transfers Crick proposes and whether Crick intended the central Dogma to be a positive hypothesis describing how a process is done
Three Classifications of Information Transfers Crick Proposes
Crick proposes three classifications of information transfer based on the central dogma of molecular biology dealing with detailed residue by residue sequential information transfer. Such information cannot be transferred from protein to protein or the nucleic acid. These three classification of information transfers are the general, special, and unknown transfers. The general information transfer can occur in all cells, and has the following cases DNA → DNA, DNA → RNA, and RNA → Protein. On the other hand a special transfer doesn’t occur in most cells, but may sometimes occur in circumstances that are special. It has these possible candidates RNA → RNA, RNA → DNA, DNA → Protein (Crick, 1970). Lastly, the unknown transfers are those that are believed to never occur, and they are: Protein → Protein, Protein → DNA, and Protein → RNA. Whether Crick intended the Central Dogma to be a positive hypothesis and details of how a process is done or a hypothesis ruling out a process.
Crick intended the central Dogma to be a positive hypothesis through the presentation of sequence Hypothesis General Principle where he assumed that specificity of a nucleic acid piece is expressed majorly by the bases sequence and that the sequence is a simple code for amino acids sequence for a specific protein. Additionally, crick described the...