Metabolic Research (Essay Sample)

METABOLIC RESEARCH
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The research article, Comparison and correlation of candidal colonization in diabetic patients and normal individuals, Pallavan et al, is off the open access peer-reviewed Journal of Diabetes & Metabolic Disorders. The research bases its study on the effects of the body resistance mechanisms for diabetic and normal individuals on secondary infections.
Background
Endocrine disorders are normally communal within the universe. Thus, a common endocrine disorder takes the form of diabetes mellitus. Moreover, diabetes mellitus normally weakens the body’s defense system to underlying infections (Pallavan et al, 2014). As a result, there are infections that opportunistic and attack the host in colonies. In comparison to the effect of these infections on normal healthy individuals, the effect on diabetic individuals is adverse. Oral candidiasis is an infection that attacks individuals invaded by the fungus Candida albicans (Barnes, 2006). This infection occurs in colonies and the rigorousness of their spread in blood differs with individuals. The rate is higher in diabetic individuals as compared to normal individuals.
Research Purpose
The research aims to establish the effects that diabetics has in the spread of oral candidiasis in the host blood.
Research Population
The research covers two population samples; healthy individuals and diabetic individuals.
Aspects of the Research
The research aims to define the aspects of diabetics that aid in the spread of oral candidiasis. The key aspect is the effect diabetes has on the immune system of the body.
Method and Results
The research utilizes the cytological techniques of oral exfoliation in data collection. Two test samples with a definite sample population are demarcated (Barnes, 2006). The two test samples are; normal individuals and diabetic individuals. The test involves tallying of the age and gender of the two test samples for a common base (Pallavan et al, 2014). The research is ethically undertaken with the underlying accord of the sample inhabitants is a study demand. A brief medical history for the individuals provides the basis for exclusion. The individual with rare deficiencies, other endocrine disorders; immunodeficiency, and chronic ailments are left out the sample population list.
The mucosa linings within the mouth commonly emit the test sample. The reagent, which is the Periodic Acid Schiff, depicts the degree of annexation of the verbalized candidiasis (Barnes, 2006). The microscope helps in the examination of the prevailing oral candidiasis colonies. Under specific test parameters, the result analysis employs statistical techniques to draw out test patterns. The underlying method commonly used is the Chi-square test. The Chi-square test shows major variations in the oral candidiasis colonies for diabetic and normal individuals (Pallavan et al, 2014). The foundation is noticeable in the diabetics when related to corresponding normal individuals.
Limitations of Research
The population for research is limited to diabetic and normal individuals. The screening process in the sample selection process eliminates individuals with other ailments. The research is a scientific process and therefore involves few people in the sample population. It is costly to conduct research on huge sample populations.
Threats to Internal/External Validity
The research technique is valid in regard to gathering and testing of the underlying samples. However, threats occur in the ethical and stereotypic contexts (Barnes, 2006). Seclusion of the diabetic personalities is normally perceived by corresponding diabetics as mainly stereotypic. The scientific methods in the research meet societal resistance as they are viewed as unethical in some societies.
Relevancy to PT Practice
Oral candidiasis is an ailment that relates to physical therapy practice. The research recommends early diagnosis to determine the necessary steps in curbing the a...