Discussion Post on Cholinesterase Inhibitors (Essay Sample)

Student’s Name Professor’s Name Course Number Date Discussion Post on Cholinesterase Inhibitors Cholinesterase inhibitors, such as donepezil, are a frequent treatment for Alzheimer's and other kinds of dementia. The levels of the neurotransmitter acetylcholine that are found in the brain are increased due to these medications. A shortage of this neurotransmitter, considered essential to proper brain operation, is frequently blamed for the cognitive impairments associated with these illnesses. Donepezil acts as an enzyme inhibitor, preventing the cholinesterase enzyme from functioning normally. In the brain, an enzyme known as cholinesterase is often responsible for the degradation of acetylcholine (Kumar 219). Donepezil can stop the enzyme from performing its job. Acetylcholine's capacity to stay in the brain for a longer time, improving the neurotransmitter's function, can be increased by doing these steps. According to one piece of research, the drug donepezil helped patients with Alzheimer's disease think more clearly and delayed the condition's advancement. By increasing the amount of acetylcholine in the brain, donepezil may make it easier for brain cells to use the neurotransmitter acetylcholine. Therefore, the utilization of acetylcholine in brain cells is increased, resulting in improved cognitive function and delayed development of dementia. Donepezil is often provided to patients with moderate to severe Alzheimer's disease and is intended to be administered once a day (Kumar 223). Patients who are experiencing a significant number of Alzheimer's symptoms should not use donepezil since there is a possibility that it will make their condition much worse. Donepezil has the potential to bring on stomach problems, including nausea, vomiting, and diarrhea, when used with other drugs. This indi...