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Health, Medicine, Nursing
Gastrointestinal Hormones in Digestion Nursing Article (Article Sample)
It was an article meant to give out a scope of information concerning endocryne system.source..
NAME:MOTATIRO CHACHA EMMANUEL
REGISTRATION NUMBER: I411/1305/2013
COURSE:BIOCHEMISTRY AND MOLECULAR BIOLOGY
A)DISCUSS THE BIOSYNTHESIS, SECRETION AND ROLES OF GASTROINTESTINAL HORMONES IN DIGESTION. (15 Marks)
Gastrointestinal hormones constitutes a group of hormones secreted by enteroendocrine cells in the stomach, pancreas and small intestine that controls various functions of the digestive organs. Enteroendocrine cells do not form glands but are spread throughout the digestive tract. They exert their autocrine and paracrine actions that integrate gastrointestinal function.
It is secreted when the stomach is empty. It enters the bloodstream and affects a part of the brain known as the hypothalamus which governs appetite. Gherin is a peptide hormone releasesd from the stomach and liver and is often called “hunger hormone” since high levels of it are found in individuals who are fasting. Gherin agonistic treatment can be used to treat illness such as loss of appetite in cancer patients. It is also used in the treatment of obesity.
This hormone is secreted and released by the enteroendocrine cells in the duodenum, the first segment of the small intestine. Its presence causes the release of digestive enzymes and bile from the pancreas and gall bladder and also acts as a hunger suppressant, it also catalyses the digestion of fats, protein and carbohydrates.
This hormone is synthesized and secreted by enteroendocrine cells in the mucosal lining of the small intestine found in the duodenum and jejunum called I cells. Cholecystokinin plays a major role in induction of the gall bladder contraction, stimulates secretion of pancreatic enzymes, insulin, glucagon and pancreatic polypeptides. It also plays a role in indicating satiety. The C-terminal 8 amino acid peptide cholecystokinin-8 retains full activity.
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