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Dissertation Review
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Blood Culture (Dissertation Review Sample)


the paper deals with the literature review of blood culture


Blood Culture
Student’s Name:
Blood culture is when a sample of blood is taken for test in the laboratory where is it put in a special container or dish and watched to see whether there are some germs contained in it. If some form of bacteria are indicated, further investigation if done to identify the specific type of the bacteria. Various methods can be used. Such methods are like; a gram stain which is used to identify microorganisms by a special series of stains. Blood culture is therefore so important. The following are some of the studies that have been in blood culture.
Literature Review
Murphy, (2013). Investigating the impact of blood culture bundles on the incidence of blood culture contamination Rates. Journal of the association for vascular access, 18 (14), 217
The aim of the study was to assess blood culture bundles on the blood culture infectivity rates when blood culture was found through an essential venous access device. The study uses pre audits and post audits intervention designs that are not experimental. During the study, a comparison of contamination between the pre audit rates and post audit rates was made the blood culture bundle had been introduced. After the comparison another comparison of the mean the results from the two audits was also made. This was done by using a bivariate statistical t- test. According to the results, it was clear that there was a sixty one percent decrease in the rates of contamination where a blood culture bundle was used to get a sample for a CVAD. A proportion p-value of 0.0404 was indicated by the obtained results.
Limitations of the Study
Due to some reasons, the study had some limitations which are as follows; there was a laboratory personnel technique to investigate the blood samples, it was impossible to read the handwriting on the labels of specimen, not able to easily maintain accessible supply of blood culture bundles. After the study, it was emphasized that proper utilization of blood culture bundle be emphasized in order to get a sample of blood from a CVAD was important for a care of high quality standard. A policies and some procedure s were therefore made to make sure those standard of care were achieved. It was seen that implementing the blood culture bundle was seen as an effective measure to reduce; the cases of unrealistic good results , high costs of microbiological testing, slow patient care, good else of therapy and period of stay.
Willekens, C. (2013), Bone marrow necrosis: a culture medium for bacteria, blood journal, 122 (16), 2775-2775
In his study, aim of this study was to investigate the medium culture for bacterial. In his article, Willekens focuses on the different types of bacteria and their possible effects. During the study, a man of 71 years old who according to medical history he had a gastric den carcinoma had been hospitalized and treated by surgery two years ago. The man had been taken to hospital with a lot of care for septic shock because of streptococcus. He had an astonished back and pelvis pain before the septic shock. The results of the blood cell count revealed hemoglobin of 8.9 g/Dl, Platelets 36, white blood cells 9.87 and erythromylemia. Some other biological findings revealed elevated lactate phosphate and dehydrogenate, iliac bone marrow and sterna. Dark smears were discovered by the aspiration after coloration. Another evaluation was also done through the microscope. This evaluation revealed that there were disintegrated cell, and some bacteria which were surrounded by a microscopic evaluation showed disintegrated Cells, psychotic nuclei and bacteria surrounded by a background of materials of amorphous extracellular.
The data collected was then analyzed. After data analysis, also the findings indicated presence of S gallolyticu. The analysis revealed that there were metastatic cells of gastric origin. The diagnosis bones marrow necrosis and secondary bone marrow infection because septicemia had been retained. The diagnosis of bone marrow necrosis contained some sepsis and modularly metastasis of gastric adenocarcinoma. Apart from ant biotherapy, there is no other particular treatment that was taken. The patient eventually died later after three days. According to the study, Bonn carcinoma e marrow necrosis is an uncommon disorder mostly associated with acute leukemia and solid cancer.
Roenblum, J. & Levy, A. (2014) RE: Repeating blood culture in neutropenia children with persistent fevers when the initial blood culture is negative, pediatric blood cancer, 61(2)193-193
The study is about how febrile neutropenia is important for the hospitalization of pediatric oncology patients. The commencement of antibiotics and the overall reduction in rates of bacteria, would forecast low results of detection of bacteria in repetitive blood cultures. Despite the small proof supporting the value of serial cultures, recur culturing with fever still remain. In the study, a review on the records of patients with ecology who were admitted to the children’s hospital which was at Montefiore Pediatric was done. This review was done with an aim of determining the rate of continuous blood culture growth. The original blood culture showed that there was no bacterial growth. The study findings showed that there were 457 febrile neutropenia episodes in 137 patients. The original blood culture was optimistic in 84 episodes 18.4%. In 220 episodes comprising 105 patients, the original blood culture was depressing and a succeeding culture was developed. In 24 episodes growth of bacteria 10.9% was detected in the duplicate culture. Risk factors incorporated a previous history of bacteria and hospitalization for more than three days earlier to onset of fever. In patients with febrile neutropenia, bacteria is measured almost twice as regularly in original blood cultures than in repeat blood cultures obtained when the original blood culture is negative. Despite an original negative blood culture, bacteria can also be detected in more than 10% of episodes when a repeat blood culture is realized. The risk is so high for patients with an earlier history of hospitalized faction for more than prior to three days e onset of fever.
Lee K. Sog, w; Park, M, Hyun, J; Kim, H.S & Lee, K.M, (2011) Comparison of the BACTEC Peds plus pediatric blood culture bottle to the BACT/Alert PF Pediatric blood culture bottle for culturing blood from pediatric patients . Korean journal of clinical microbiology, 14 (4), 126
The study was about comparing the BACTEC Peds plus pediatric blood culture bottle to the bacteria alert. During the a study, a comparison between the BATEC Peds and Bact alert PF pediatric blood culture bottles in the framework of recovery and detection time of fungi and bacteria from patients with pediatric was done. During data collection, samples of blood were collected for traditions from pediatric patients who were in the hospital BACTEC FX and Bact/Alert 3D blood culture structure and were tested for 5 days. The results showed that 5,018 sets were evaluated. The recovery magnitude for BACTEC Peds Plus and Bact/Alert PF bottles were 57% in overall and 69% correspondingly. There was a considerable difference between the 0.38% contamination rate in Bact/Alert PF bottles and the 0.16% contamination rate in BACTEC Peds Plus bottles. The average TTD for all microorganisms was extensively reduced for the BACTEC Peds Plus bottles, but was increased for Candida parapsilosis compared to the results for the Bact/Alert PF bottles. The study indicated that the rate of detection and infectivity is high when Bact/Alert PF bottles are used than when BACTEC Peds Plus bottles are used for pediatric blood culture. The BACTEC Peds Plus bottles almost detect all enrolled microorganisms extensively faster than do the Bact/Alert PF bottles.
Roth, A. (2010). The connector or not the connector: Reduction of blood culture contamination, American journal of infection control, 38 (5) e 76-e77
The study is aimed at comparing different cultures. The cultures compared in the study are; the true negative and false positive blood cultures. According to the study, the false positive cultures also prolong the length of stay for patients apart from their increase in laboratory work. The false positive blood cultures also help patients to use several spectrum antibiotics of which all of them can raise the antibiotic resistance and patient morbidity. The study evaluated the results of uncomplicated informational intervention intended at lowering blood culture contamination at Skåne University Hospital (SUS), Malmo, Sweden, throughout 3.5 months, focusing on responsible departments for collecting a lot of blood cultures. The findings of the study were then analyzed by using a multivariate logistic regression model pre- and post intervention contamination rates, analyzed with a multivariate logistic regression model to obtain important determinants of contamination. According to the study, 51,264 blood culture sets resulted from 14,826 patients. The blood culture contamination rate pre intervention was 2.59% and reduced to 2.23% post intervention. A similar reduction in related bacterial isolates was not found. Contamination rates at three secondary hospitals did not diminish in the same era. The outcome of the intervention on phlebotomists' understanding of blood culture routines was also evaluated, with a clear raise in level of understanding among interviewed phlebotomists post intervention. The study shows that a comparatively simple informational intervention can have considerable effects on the contaminated blood cultures level, even in a situation with low rates of contamination where nurses and supplementary nurses perform phlebotomies.
Miller, N.S , D Rogan, B.L, Orr & Whitney, (2011); Comparison of BD BACTEC plus blood culture mediator versa ...
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