Advanced Pharmacology (Essay Sample)

Week 5 Case Study NSG6005 Advanced Pharmacology Student’s Name Institutional Affiliation Course Number: Course Title Instructor’s Name Assignment Due Date Week 5 Case Study NSG6005 Advanced Pharmacology Question 1 Low-dose thiazide diuretics are the primary method of treating hypertension. In terms of reduced mortality and increased life expectancy, this class of drugs is the most effective. First-line therapy often consists of thiazide diuretics because to its low cost, high efficacy, and generally good safety profile (Khong, & Adeyeye, 2019). Early detection of hypertension may also benefit from the use of beta-blockers, even though they should not be used alone to treat the condition (Wiysonge et al., 2017). Thiazide diuretics, beta-blockers, and vasodilators are the standard of care for individuals without preexisting cardiac conditions. A thiazide plus a beta-blocker are all that is needed to treat comorbidities like STEMI and heart failure. Calcium channel blockers and angiotensin-converting enzyme inhibitors might be used as a backup plan if the first treatment regimen doesn't provide the desired results (Rosenthal, & Burchum, 2021). Question 2 Calcium channel blockers in combination with thiazide diuretics are the treatment of choice for the majority of African Americans (Helmer, Slater, & Smithgall, 2018). There are three distinct pharmaceutical combinations that have worked for this group. ACE inhibitors and thiazide diuretics, beta-blockers and a thiazide diuretic, and ACE inhibitors and calcium channel blockers all include the three different medication sequences that have been shown to be effective for this group's hypertension. If the calcium channel blockers and thiazide diuretics does not control their hypertension, then one of the other two medicatio...