Inflammatory Bowel Disorder (IBD) and Irritable Bowel Syndrome (IBS) (Essay Sample)

Inflammatory Bowel Disorder (IBD) and Irritable Bowel Syndrome (IBS)
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Inflammatory Bowel Disorder (IBD) and Irritable Bowel Syndrome (IBS)
IBS refers to a chronic remittent gastrointestinal functional disorder characterized by bowel disturbance, abdominal pain and bloating. It encompasses a number of symptoms and its pathophysiology is quite complicated. The current pathophysiological mechanisms of IBS include abnormal gut motility, nervous system dysfunction and visceral sensitivity (Lee & Park, 2014). The interactions that occur between the three mechanisms make the bowel susceptible to many factors such as genetic predisposition. IBD, on the other hand, include a group of inflammatory conditions where the body’s immune system aggressively attacks some parts of the digestive system. Its pathophysiological mechanisms include Crohn diseases and ulcerative colitis (Michielan & D’Incа, 2015).
Similarities and Differences between IBD and IBS
Whereas IBD is characterized by organic changes such as ulcerations in the large and small intestine, IBS is characterized as a functional bowel disorder. Secondly, IBS is identified as a non-inflammatory condition while IBD causes chronic swelling of the bowel (Michielan & D’Incа, 2015). IBD is more common as compared to IBD. However, both IBD and IBS lead to constipation, urgent movement of the bowel, and abdominal pain (Guandalini et al., 2014).
Common Treatments for IBD and IBS
Treatments for IBD include use of antibiotics such as ciphroflora, immunomodulators such as methotrexate, and biologic therapies (Michielan & D’Incа, 2015). Treatments for IBS include use of laxatives, anti-diarrheal agents, probiotics and fiber supplements (Lee & Park, 2014). Use of antibiotics would work for both of the disorders.
How Genetics Affect Pathophysiology of IBD and IBD
The genetic influence on these disorders is based on genetic epidemiological studies, familial aggregation and twin studies. Majority of IBS and IBD patients report family history of the disorders. Secondly, twin studies has indicated a higher concordance rate for IBD and IBS in monozygotic twins as compared to dizygotic twins (Guandalini et al., 2014). Lastl...