Chemoselective partial reduction of amides in the presence of esters to form aldehydes by using a new copperdiisobutyl-t-butoxyaluminum hydride (CDBBA) reagent (Research Paper Sample)

0bottomDepartment of Chemistry, Kangwon National University, and Institute for Molecular Science and Fusion Technology, Chuncheon 200-701, Korea. Fax: +82-33-253-7582; Tel: +82-33-250-8494; E-mail: dkan@kangwon.ac.krAddress here.† Footnotes relating to the title and/or authors should appear here.Electronic Supplementary Information (ESI) available: [details of any supplementary information available should be included here]. See DOI: 10.1039/x0xx00000x020000Department of Chemistry, Kangwon National University, and Institute for Molecular Science and Fusion Technology, Chuncheon 200-701, Korea. Fax: +82-33-253-7582; Tel: +82-33-250-8494; E-mail: dkan@kangwon.ac.krAddress here.† Footnotes relating to the title and/or authors should appear here.Electronic Supplementary Information (ESI) available: [details of any supplementary information available should be included here]. See DOI: 10.1039/x0xx00000x N Received 00th January 20xx,
Accepted 00th January 20xx
DOI: 10.1039/x0xx00000x
www.rsc.org/
Chemoselective Partial partial Rreduction of Aamides in the presence of esters to form Aaldehydes over Esters withby using a new Ccopper Ddiisobutyl-t-butoxyaluminum Hhydride (CDBBA) reagent.
So Hee Im, Won Kyu Shin, Ashok Kumar Jaladi and Duk Keun An*
A new and efficient reducing agent system, copperdiisobutyl-t-butoxyaluminum hydride (CDBBA), was readily prepared by the reaction of versatile reagent lithium diisobutyl-t-butoxyaluminum hydride (LDBBA) with copper iodide (CuI). was described for theCDBBA was capable of carrying out the chemoselective partial reduction of amides to aldehydes, within excellent yields at ambient temperature. In additionAdditionally, this system provides provided a straight forward method for uncommon chemoselective partial reduction reactions of amides over esters.