Sign In
Not register? Register Now!
Essay Available:
Pages:
2 pages/≈550 words
Sources:
11 Sources
Level:
APA
Subject:
Biological & Biomedical Sciences
Type:
Research Paper
Language:
English (U.S.)
Document:
MS Word
Date:
Total cost:
$ 11.66
Topic:

Venetoclax for Treating Chronic Lymphocytic Leukaemia Biomedical Essay (Research Paper Sample)

Instructions:

Venetoclax for Treating Chronic Lymphocytic Leukaemia

source..
Content:

Venetoclax for Treating Chronic Lymphocytic Leukaemia
Name:
Institution of affiliation:
Date:
Chronic Lymphotic Leukaemia(CLL) is the most prevalent form of leukaemia with over 3500 new diagnoses annually in the United Kingdom alone (NICE org, 2019). According to Stilgenbauer et al (2016) the landscape for treatment of the disease has in the recent past changed owing to the introduction of agents that inhibit intracellular B-cell receptor signaling. Venetoclax is a new drug in the market in treating for the disease (NICE org.). The NICE website indicates that the new treatment is used together with rituximab in the treatment of chronic lymphocytic leukaemia and small lymphocytic lymphoma for people who have already been treated using chemotherapy (Chemocare) MedScape website echoes Chemocare statement that venetoclax usually treats relapse of chronic lymphotic leukaemia after primary chemotherapy treatment). Stilgenbauer et al (2016) affirm NICE org assertion that the treatment is orally administered.  Indicators for Venetoclax in CLL include for the treatment of CLL in the presence of the del(17p) or TP53 mutation in adult patients who are unsuitable for or have not responded to a BCRi (Mistry et al (2018); and for the treatment of CLL in the absence of the del(17p) or TP53 mutation in adult patients who have not responded to both chemoimmunotherapy and a BCRi Stilgenbauer et al (2016). In its use, Mistry et al (2018) indicate that venetoclax selectively inhibits the function of BLC-2 protein hence restoring the ability of the body to trigger the body’s cancer cells self-destruct. The treatment performs this function by inducing apoptosis in vitro against primary chronic lymphotic leukaemia cells (Mistry et al, 2018).

...
Get the Whole Paper!
Not exactly what you need?
Do you need a custom essay? Order right now:

Other Topics:

  • Engineering 183EW: The Main Technological Advantage Of Dna Engineering
    Description: DNA engineering, whether it be related to food and humans, has been a controversial topic in 21st century. Since the first identification of genes in the mid-1800s, scientists have come very far....
    36 pages/≈9900 words| 68 Sources | APA | Biological & Biomedical Sciences | Research Paper |
  • Research Bitou Bush Along the New South Wales Coast
    Description: This article aims at addressing these issues and how the bitou bush impacts on the ecosystem and the importance of managing the spread of this plant since it's a hazard that is harmful to the plants, environment, and animals....
    14 pages/≈3850 words| 20 Sources | APA | Biological & Biomedical Sciences | Research Paper |
  • Transcultural Healthcare Models Research Assignemnt
    Description: Describe Purnell's 12 domains of culture, and assess how each of these domains plays an active role in the diversity of health care in your specific field...
    3 pages/≈825 words| 3 Sources | APA | Biological & Biomedical Sciences | Research Paper |
Need a Custom Essay Written?
First time 15% Discount!